Part Number: ADS1299IPAGR

Manufacturer: Texas Instruments

Description: IC AFE 8 CHAN 24BIT 64TQFP

Shipped from: Shenzhen/HK Warehouse

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Technical Specifications of ADS1299IPAGR

Datasheet  ADS1299IPAGR datasheet
Category Integrated Circuits (ICs)
Family Data Acquisition – Analog Front End (AFE)
Manufacturer Texas Instruments
Packaging Tape & Reel (TR)
Part Status Active
Number of Bits 24
Number of Channels 8
Power (Watts) 42mW
Voltage – Supply, Analog 5V
Voltage – Supply, Digital 1.8 V ~ 3.6 V
Package / Case 64-TQFP
Supplier Device Package 64-TQFP (10×10)


The ADS1299IPAGR is a cutting-edge analog-to-digital converter (ADC) that is used in electroencephalogram (EEG) studies, fetal electrocardiography (ECG), sleep study monitoring, bispectral index (BIS) monitoring, and evoked audio potential (EAP) research. This extensive guide will provide you a thorough overview of the ADS1299IPAGR, its features, applications, and how to utilize it efficiently in your projects.

Overview of the ADS1299IPAGR

The ADS1299IPAGR is a version of the ADS1299 series that provides excellent capabilities for recording analog signals with precision and low noise. Here’s a quick rundown:

  • Family Variants: The ADS1299 family contains four-channel (ADS1299), six-channel (ADS1299), and eight-channel (ADS1299) versions to meet the needs of medical instruments with varying channel counts.
  • High Resolution: With a 24-bit resolution, the ADS1299IPAGR can generate accurate and fine-grained digital representations of analog signals.
  • Low-Noise Design: This ADC is designed for low noise interference, with input-referred noise as low as 1 V peak-to-peak over a 70-Hz bandwidth. This low noise level is essential for recording fine electrical signals, especially in medical applications.
  • Programmable Gain Amplifier (PGA): The gadget has a PGA with programmable gain levels ranging from 1 to 24. This characteristic enables precise signal amplification, allowing it to accommodate a wide range of input signal amplitudes.
  • Flexible Data Rates: The ADS1299IPAGR supports data rates ranging from 250 to 16,000 samples per second (SPS), allowing you to accommodate the exact needs of your application.
  • Supply Voltage Compatibility: It can run on both unipolar and bipolar power supplies. The analog supply voltage ranges from 4.75 V to 5.25 V, while the digital supply voltage goes from 1.8 V to 3.6 V, allowing for greater device flexibility.
  • The ADC includes various built-in functions, such as a bias drive amplifier, lead-off detection capability, test signal creation, and an onboard oscillator. These properties make circuit design easier and make it more useful in medical instrumentation installations.
  • Options for Reference Voltage: Depending on their needs, users can use an internal or external reference voltage source.
  • Common Mode Rejection Ratio (CMRR): The ADC successfully suppresses common-mode interference with a CMRR of -110 dB, guaranteeing that the measured signals are accurate and trustworthy.
  • Operating Temperature Range: The device is designed to function between -40°C and +85°C, making it appropriate for a variety of environmental and medical applications.

Signal Quality and Noise Reduction

Signal quality is critical in medical instruments applications that require precise measurements. The ADS1299IPAGR includes a number of features and tactics to improve signal quality while reducing noise interference. In this section, we will look at how to use the programmable gain amplifier (PGA) to obtain optimal signal quality and efficiently handle input-referred noise.

Maximizing Signal Quality

● Choose Appropriate Gain Settings

The ADS1299IPAGR includes a built-in PGA that lets you to choose from a variety of gain settings (1, 2, 4, 6, 8, 12, or 24). Select the gain setting that best corresponds to the amplitude of the input signal. Higher gain settings can help amplify weak signals, but be careful not to enhance noise as well.

● Saturation should be avoided

Keep an eye out for signal saturation. If the input signal exceeds the dynamic range of the ADC, it might cause clipping and data loss. To avoid saturation, adjust the gain settings and input voltage levels.

● Filters to prevent aliasing

When downsampling data, use proper anti-aliasing filters to reduce high-frequency noise and avoid aliasing effects. The filter you use is determined by the required bandwidth of your measurements.

● Calibration

Calibrate the system on a regular basis to adjust for any offsets or drift in the ADC and signal conditioning circuitry. Calibration guarantees that measurements are always accurate.

Utilizing the Programmable Gain Amplifier (PGA)

The ADS1299IPAGR’s built-in PGA is a great tool for tailoring the amplification of your input signals. Here’s how to use the PGA effectively:

  • Choose the Correct Gain Level: As previously stated, select the proper gain setting based on the amplitude of your input signal. Lower gain settings are appropriate for powerful signals, whereas higher gain settings improve sensitivity to weaker signals.
  • Gain Adjustment: To get the appropriate signal-to-noise ratio (SNR), fine-tune the gain. Higher gain settings can magnify both the signal and the noise, so strike a balance that maximizes SNR.
  • Consider the following differential measurements: When feasible, use differential measures. You can efficiently cancel out common-mode noise by monitoring the voltage difference between two electrodes or inputs.

Analyze your system’s noise characteristics, including input-referred noise and system noise. This analysis can assist you in identifying sources of noise and developing measures to reduce them.

Handling Input-Referred Noise

The noise generated by the ADC and signal conditioning circuitry, which might affect the quality of your measurements, is referred to as input-referred noise. Here are the steps to dealing with input-referred noise:

  • Filtering: Before the ADC, use low-pass filters to reduce high-frequency noise components. Filter parameters should be carefully designed to balance noise reduction with signal bandwidth preservation.
  • Shielding and grounding: Grounding and shielding procedures can help to reduce electromagnetic interference (EMI) and noise pickup in the signal route.
  • Lead Configuration: To reduce common-mode noise, pay attention to lead configuration and placement. If possible, use a referential montage configuration.
  • Calibration: Calibrate the system on a regular basis to adjust for any offsets or drift in the signal chain, which can assist decrease noise issues.

Implement signal averaging techniques to boost SNR, especially when dealing with low-amplitude sources. Averaging many samples can help to lessen the effects of random noise.

When employing the ADS1299IPAGR in medical instrumentation applications, you may enhance signal quality by carefully selecting gain levels, applying appropriate noise reduction procedures, and knowing the characteristics of input-referred noise. In disciplines such as EEG investigations, ECG monitoring, and other healthcare applications, maintaining excellent signal quality is critical for accurate and trustworthy data collecting.

Applications of the ADS1299IPAGR

  • Electroencephalogram (EEG) Study
  • Fetal Electrocardiography (ECG)
  • Sleep Study Monitoring
  • Bispectral Index (BIS) Monitoring
  • Evoked Audio Potential (EAP) Research


Engineers and researchers in the realm of medical instruments benefit from the ADS1299IPAGR, which is noted for its precision, low noise, and versatility. It is crucial in critical healthcare applications because it ensures accurate data for diagnosis, research, and monitoring.

Prioritize gain settings, noise reduction, and signal quality while using the ADS1299IPAGR. Its potential is maximized by regular calibration and in-depth comprehension. Whether you’re an engineer, researcher, or healthcare practitioner, this guide will help you navigate the ADS1299IPAGR’s complexities.

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